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Concept information

Terme préférentiel

Trimetrexate  

Type

  • mesh:Descriptor

Définition

  • A nonclassical folic acid inhibitor through its inhibition of the enzyme dihydrofolate reductase. It is being tested for efficacy as an antineoplastic agent and as an antiparasitic agent against PNEUMOCYSTIS PNEUMONIA in AIDS patients. Myelosuppression is its dose-limiting toxic effect.

Concept générique

Synonyme(s)

  • 117381-09-6 (monohydrate, monoacetate)
  • 117381-10-9 (hydrate)
  • 2,4-Quinazolinediamine, 5-methyl-6-(((3,4,5-trimethoxyphenyl)amino)methyl)-
  • 52128-35-5 (Trimetrexate)
  • UPN4ITI8T4

Traductions

  • français

  • 117381-09-6 (monohydrate, monoacetate)
  • 117381-10-9 (hydrate)
  • 2,4-Quinazolinediamine, 5-methyl-6-(((3,4,5-trimethoxyphenyl)amino)methyl)-
  • 52128-35-5 (Trimetrexate)
  • UPN4ITI8T4

URI

http://data.loterre.fr/ark:/67375/JVR-L7C0GXDV-T

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RDF/XML TURTLE JSON-LD Date de création 25/01/1991, dernière modification le 24/05/2017