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Concept information

... > Genetic Phenomena > Genetic Structures > Genome > Genome Components > Genes > Genes, Neoplasm > Oncogenes > Proto-Oncogenes > Genes, myb

Terme préférentiel

Genes, myb  

Type

  • mesh:Descriptor

Définition

  • Retrovirus-associated DNA sequences (v-myb) originally isolated from the avian myeloblastosis and E26 leukemia viruses. The proto-oncogene c-myb codes for a nuclear protein involved in transcriptional regulation and appears to be essential for hematopoietic cell proliferation. The human myb gene is located at 6q22-23 on the short arm of chromosome 6. This is the point of break in translocations involved in T-cell acute lymphatic leukemia and in some ovarian cancers and melanomas. (From Ibelgaufts, Dictionary of Cytokines, 1995).

Concept générique

Concepts associés

Synonyme(s)

  • myb Genes

Qualificatif(s) autorisé(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-KZZG7LGJ-K

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RDF/XML TURTLE JSON-LD Date de création 03/11/1999, dernière modification le 08/07/2008