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Concept information

Terme préférentiel

Amiloride  

Type

  • mesh:Descriptor

Définition

  • A pyrazine compound inhibiting SODIUM reabsorption through SODIUM CHANNELS in renal EPITHELIAL CELLS. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with DIURETICS to spare POTASSIUM loss. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p705)

Concept générique

Synonyme(s)

  • 17440-83-4 (Amiloride Hydrochloride)
  • 2016-88-8
  • 2609-46-3 (Amiloride)
  • 7DZO8EB0Z3
  • FZJ37245UC
  • Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-

Traductions

  • français

  • 17440-83-4 (Amiloride Hydrochloride)
  • 2016-88-8
  • 2609-46-3 (Amiloride)
  • 7DZO8EB0Z3
  • FZJ37245UC
  • Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-

URI

http://data.loterre.fr/ark:/67375/JVR-KLVK0P10-2

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RDF/XML TURTLE JSON-LD Date de création 01/01/1999, dernière modification le 24/05/2017