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Concept information

... > Carbohydrates > Glycosides > Cardiac Glycosides > Cardenolides > Digitalis Glycosides > Digoxin
... > Polycyclic Compounds > Fused-Ring Compounds > Steroids > Cardanolides > Cardiac Glycosides > Cardenolides > Digitalis Glycosides > Digoxin

Terme préférentiel

Digoxin  

Type

  • mesh:Descriptor

Définition

  • A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone DIGOXIGENIN. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in ATRIAL FIBRILLATION and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic doses is small. (From Martindale, The Extra Pharmacopoeia, 30th ed, p666)

Concept générique

Concepts spécifiques

Synonyme(s)

  • 20830-75-5 (Digoxin)
  • 73K4184T59
  • Card-20(22)-enolide, 3-((O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl)oxy)-12,14-dihydroxy-, (3beta,5beta,12beta)-

Qualificatif(s) autorisé(s)

Action(s) pharmacologique(s)

Traductions

  • Digoxine

    français

  • 20830-75-5 (Digoxin)
  • 73K4184T59
  • Card-20(22)-enolide, 3-((O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl)oxy)-12,14-dihydroxy-, (3beta,5beta,12beta)-

URI

http://data.loterre.fr/ark:/67375/JVR-KK47152P-8

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RDF/XML TURTLE JSON-LD Date de création 01/01/1999, dernière modification le 24/05/2017