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Concept information

Terme préférentiel

Platelet Glycoprotein GPIb-IX Complex  

Type

  • mesh:Descriptor

Définition

  • Platelet membrane glycoprotein complex essential for normal platelet adhesion and clot formation at sites of vascular injury. It is composed of three polypeptides, GPIb alpha, GPIb beta, and GPIX. Glycoprotein Ib functions as a receptor for von Willebrand factor and for thrombin. Congenital deficiency of the GPIb-IX complex results in Bernard-Soulier syndrome. The platelet glycoprotein GPV associates with GPIb-IX and is also absent in Bernard-Soulier syndrome.

Synonyme(s)

  • Glycoprotein Ib-IX Complex

Traductions

  • français

  • Complexe glycoprotéine-Ib-IX de membrane plaquettaire
  • Complexe glycoprotéique GP-Ib-IX plaquettaire
  • Complexe glycoprotéique Ib-IX
  • Complexe GP-Ib-IX plaquettaire
  • Complexe GPIb-IX de membrane plaquettaire

URI

http://data.loterre.fr/ark:/67375/JVR-JVCH8CT1-0

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RDF/XML TURTLE JSON-LD Date de création 26/05/1995, dernière modification le 25/06/2015