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Concept information

... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Molecular Conformation > Protein Conformation > Protein Structural Elements > Amino Acid Motifs > Immunoreceptor Tyrosine-Based Inhibition Motif
... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Molecular Conformation > Protein Conformation > Protein Structure, Secondary > Amino Acid Motifs > Immunoreceptor Tyrosine-Based Inhibition Motif

Terme préférentiel

Immunoreceptor Tyrosine-Based Inhibition Motif  

Type

  • mesh:Descriptor

Définition

  • A conserved AMINO ACID SEQUENCE located in the intracellular domains of a family of transmembrane proteins that negatively regulate the signal transduction processes emanating from transmembrane proteins containing IMMUNORECEPTOR TYROSINE-BASED ACTIVATION MOTIFS. The CONSENSUS SEQUENCE of this motif is I(or V)LXYXXL(or V) (where X denotes any amino acid). Also known as ITIM motifs.

Concept générique

Synonyme(s)

  • Immune Receptor Tyrosine-Based Inhibition Motif
  • Immuno-Receptor Tyrosine-Based Inhibition Motif

Qualificatif(s) autorisé(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-HTRMN606-4

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RDF/XML TURTLE JSON-LD Date de création 03/07/2012, dernière modification le 05/07/2016