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Concept information

Diagnosis > Diagnostic Techniques and Procedures > Clinical Laboratory Techniques > Cytological Techniques > Patch-Clamp Techniques
Investigative Techniques > Clinical Laboratory Techniques > Cytological Techniques > Patch-Clamp Techniques

Terme préférentiel

Patch-Clamp Techniques  

Type

  • mesh:Descriptor

Définition

  • An electrophysiologic technique for studying cells, cell membranes, and occasionally isolated organelles. All patch-clamp methods rely on a very high-resistance seal between a micropipette and a membrane; the seal is usually attained by gentle suction. The four most common variants include on-cell patch, inside-out patch, outside-out patch, and whole-cell clamp. Patch-clamp methods are commonly used to voltage clamp, that is control the voltage across the membrane and measure current flow, but current-clamp methods, in which the current is controlled and the voltage is measured, are also used.

Concept générique

Synonyme(s)

  • Patch-Clamp Technic
  • Patch-Clamp Technics
  • Patch Clamp Technique
  • Patch-Clamp Technique

Qualificatif(s) autorisé(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-GLTVLHM8-6

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RDF/XML TURTLE JSON-LD Date de création 25/01/1994, dernière modification le 27/05/2020