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Concept information

Terme préférentiel

Immunoglobulin Joining Region  

Type

  • mesh:Descriptor

Définition

  • A segment of the immunoglobulin heavy chains, encoded by the IMMUNOGLOBULIN HEAVY CHAIN GENES in the J segment where, during the maturation of B-LYMPHOCYTES; the gene segment for the variable region upstream is joined to a constant region gene segment downstream. The exact position of joining of the two gene segments is variable and contributes to ANTIBODY DIVERSITY. It is distinguished from the IMMUNOGLOBULIN J CHAINS; a separate polypeptide that serves as a linkage piece in polymeric IGA or IGM.

Concept générique

Synonyme(s)

  • Joining Region, Ig

Action(s) pharmacologique(s)

Traductions

  • français

  • Région charnière d'immunoglobuline
  • Région charnière des immunoglobulines
  • Région jonction d'immunoglobuline
  • Séquence jonction d'immunoglobuline

URI

http://data.loterre.fr/ark:/67375/JVR-FWZW3LMT-X

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RDF/XML TURTLE JSON-LD Date de création 11/05/1987, dernière modification le 25/06/2010