Passer au contenu principal

Medical Subject Headings (thesaurus)

Choisissez le vocabulaire dans lequel chercher

  • Aide
aligner
annoter
télécharger

Concept information

... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Molecular Conformation > Protein Conformation > Protein Structural Elements > Protein Domains > Discoidin Domain
... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Molecular Conformation > Protein Conformation > Protein Structure, Tertiary > Protein Domains > Discoidin Domain

Terme préférentiel

Discoidin Domain  

Type

  • mesh:Descriptor

Définition

  • A protein domain originally identified in DISCOIDINS. It occurs in a variety of unrelated proteins in multicellular organisms, where it recognizes different ligands with distinct biological functions. Structurally, it consists of two antiparallel beta sheets that form a "jellyroll" configuration stabilized by two intramolecular disulfide bonds. Sequence differences within this module determine ligand specificity; in DISCOIDIN DOMAIN RECEPTORS, it binds to FIBRILLAR COLLAGENS and NON-FIBRILLAR COLLAGENS.

Concept générique

Synonyme(s)

  • Discoidin Domains

Qualificatif(s) autorisé(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-DKF52SD9-T

Télécharger ce concept :

RDF/XML TURTLE JSON-LD Date de création 08/07/2016, dernière modification le 09/05/2016