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Medical Subject Headings (thesaurus)

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Concept information

Terme préférentiel

Simvastatin  

Type

  • mesh:Descriptor

Définition

  • A derivative of LOVASTATIN and potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It may also interfere with steroid hormone production. Due to the induction of hepatic LDL RECEPTORS, it increases breakdown of LDL CHOLESTEROL.

Concept générique

Synonyme(s)

  • 79902-63-9 (Simvastatin)
  • AGG2FN16EV

Traductions

  • français

  • 79902-63-9 (Simvastatin)
  • AGG2FN16EV

URI

http://data.loterre.fr/ark:/67375/JVR-D9FD2HPW-B

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RDF/XML TURTLE JSON-LD Date de création 20/06/1997, dernière modification le 17/01/2017