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Concept information

Heterocyclic Compounds > Heterocyclic Compounds, 1-Ring > Pyridines > Pyridinium Compounds > 1-Methyl-4-phenylpyridinium

Terme préférentiel

1-Methyl-4-phenylpyridinium  

Type

  • mesh:Descriptor

Définition

  • An active neurotoxic metabolite of 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE. The compound reduces dopamine levels, inhibits the biosynthesis of catecholamines, depletes cardiac norepinephrine and inactivates tyrosine hydroxylase. These and other toxic effects lead to cessation of oxidative phosphorylation, ATP depletion, and cell death. The compound, which is related to PARAQUAT, has also been used as an herbicide.

Concept générique

Concepts associés

Synonyme(s)

  • 1-Methyl-4-phenylpyridine
  • 1-Methyl-4-phenylpyridinium Ion
  • 39794-99-5 (chloride)
  • 48134-75-4 (1-Methyl-4-phenylpyridinium)
  • Cyperquat
  • MRP3DNB9K9
  • N-Methyl-4-phenylpyridine
  • N-Methyl-4-phenylpyridinium
  • Pyridinium, 1-methyl-4-phenyl-
  • R865A5OY8J

Qualificatif(s) autorisé(s)

Action(s) pharmacologique(s)

Traductions

  • 1-Méthyl-4-phényl-pyridinium

    français

  • 1-Méthyl-4-phénylpyridinium
  • 39794-99-5 (chloride)
  • 48134-75-4 (1-Methyl-4-phenylpyridinium)
  • MRP3DNB9K9
  • Pyridinium, 1-methyl-4-phenyl-
  • R865A5OY8J

URI

http://data.loterre.fr/ark:/67375/JVR-C8FKRNNN-9

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RDF/XML TURTLE JSON-LD Date de création 16/05/1989, dernière modification le 27/05/2016