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von Willebrand Factor  

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Tipo

  • mesh:Descriptor

Definición

  • A high-molecular-weight plasma protein, produced by endothelial cells and megakaryocytes, that is part of the factor VIII/von Willebrand factor complex. The von Willebrand factor has receptors for collagen, platelets, and ristocetin activity as well as the immunologically distinct antigenic determinants. It functions in adhesion of platelets to collagen and hemostatic plug formation. The prolonged bleeding time in VON WILLEBRAND DISEASES is due to the deficiency of this factor.

Concepto genérico

Etiquetas alternativas

  • Factor VIIIR-Ag
  • Factor VIII-Related Antigen
  • Factor VIIIR-RCo
  • Ristocetin Cofactor
  • Ristocetin-Willebrand Factor
  • von Willebrand Protein

En otras lenguas

URI

http://data.loterre.fr/ark:/67375/JVR-TJ0M8L4L-3

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RDF/XML TURTLE JSON-LD Creado 25/7/75, última modificación 6/7/09