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Nervous System Diseases > Nervous System Malformations > Malformations of Cortical Development > Malformations of Cortical Development, Group II > Lissencephaly
... > Congenital, Hereditary, and Neonatal Diseases and Abnormalities > Congenital Abnormalities > Nervous System Malformations > Malformations of Cortical Development > Malformations of Cortical Development, Group II > Lissencephaly

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Lissencephaly  

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Tipo

  • mesh:Descriptor

Definición

  • A smooth brain malformation of the CEREBRAL CORTEX resulting from the abnormal location of developing neurons during corticogenesis. It is characterized by an absence of normal convoluted indentations on the surface of the brain (agyria), or fewer and shallower indentations (pachygryia). There is a reduced number of cortical layers, typically 4 instead of 6, resulting in a thickened cortex, and reduced cerebral white matter that is a reversal of the normal ratio of cerebral white matter to cortex.

Concepto genérico

Conceptos específicos

Etiquetas alternativas

  • Lissencephalia

En otras lenguas

URI

http://data.loterre.fr/ark:/67375/JVR-TCCWCDFH-J

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RDF/XML TURTLE JSON-LD Creado 9/7/07, última modificación 26/2/16