Concept information
Término preferido
Valosin Containing Protein
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Tipo
-
mesh:Descriptor
Definición
- A highly-conserved AAA ATPase that functions in the biogenesis of the transitional ENDOPLASMIC RETICULUM and fragmentation and reassembly of the GOLGI APPARATUS during MITOSIS. It also functions in a complex with UFD1L and NPLOC4 proteins to export misfolded ubiquitinated proteins from the endoplasmic reticulum and outer mitochondrial membrane to the cytoplasm for degradation by the PROTEASOME and also plays a role in AUTOPHAGY of ubiquitinated proteins. It occurs in neuronal INCLUSION BODIES from patients with AMYOTROPHIC LATERAL SCLEROSIS and LEWY BODIES from PARKINSON DISEASE patients.
Concepto genérico
Etiquetas alternativas
- CDC48 Protein
- Cell Cycle Protein CDC48
- Cell Cycle Protein CDC48p
- p97 Valosin-Containing Protein
- Valosin-Containing Protein
- Valosine-Containing Protein
En otras lenguas
-
francés
-
Protéine CDC48
-
Protéine contenant de la valosine
-
Protéine du cycle cellulaire CDC48
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Protéine du cycle cellulaire CDC48p
-
Protéine p97 contenant la valosine
URI
http://data.loterre.fr/ark:/67375/JVR-SSF3R6BN-S
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