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Calcineurin  

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Tipo

  • mesh:Descriptor

Definición

  • A CALCIUM and CALMODULIN-dependent serine/threonine protein phosphatase that is composed of the calcineurin A catalytic subunit and the calcineurin B regulatory subunit. Calcineurin has been shown to dephosphorylate a number of phosphoproteins including HISTONES; MYOSIN LIGHT CHAIN; and the regulatory subunits of CAMP-DEPENDENT PROTEIN KINASES. It is involved in the regulation of signal transduction and is the target of an important class of immunophilin-immunosuppressive drug complexes.

Concepto genérico

Etiquetas alternativas

  • Protein Phosphatase 3
  • Protein Phosphatase-2B

En otras lenguas

  • francés

  • PP2B
  • Protein Phosphatase 3
  • Protein Phosphatase-2B
  • Protéine-phosphatase-2B
  • Protéine-phosphatase-3

URI

http://data.loterre.fr/ark:/67375/JVR-SQL3LLX9-0

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