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Apoptotic Protease-Activating Factor 1  

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Tipo

  • mesh:Descriptor

Definición

  • A CARD signaling adaptor protein characterized by an N-terminal CARD DOMAIN and C-terminal WD40 REPEATS. It plays a role in the mitochondria-stimulated apoptosis (APOPTOSIS, INTRINSIC PATHWAY) and binds to CYTOCHROME C in the CYTOSOL to form an APOPTOSOMAL PROTEIN COMPLEX which activates INITIATOR CASPASES such as CASPASE 9.

Etiquetas alternativas

  • Apaf-1 Protease-Activating Factor
  • Apoptotic Peptidase Activating Factor 1

En otras lenguas

URI

http://data.loterre.fr/ark:/67375/JVR-SNBGGWV9-6

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