Concept information
Término preferido
ADAM17 Protein
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Tipo
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mesh:Descriptor
Definición
- A disintegrin and metalloproteinase domain-containing protein that cleaves the membrane-bound precursor of TUMOR NECROSIS FACTOR-ALPHA to its mature form. It cleaves several other CELL SURFACE PROTEINS, including INTERLEUKIN-1 RECEPTOR TYPE II; TRANSFORMING GROWTH FACTOR ALPHA; L-SELECTIN; MUCIN-1; and AMYLOID BETA-PROTEIN PRECURSOR. It can also function as an activator of the Notch signaling pathway by mediating the cleavage of NOTCH RECEPTORS.
Concepto genérico
Etiquetas alternativas
- ADAM-17
- ADAM-17 Protein
- CD156b Antigen
- Disintegrin and Metalloproteinase Domain-Containing Protein 17
- TACA (Enzyme)
- TACE (Enzyme)
- TNF-alpha Convertase
- TNF-alpha Converting Enzyme
- Tumor Necrosis Factor Alpha Convertase
- Tumor Necrosis Factor-alpha Convertase
- Tumor Necrosis Factor-alpha Converting Enzyme
En otras lenguas
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francés
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ADAM-17
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Antigène CD156b
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CD156b
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Convertase du facteur de nécrose tumorale alpha
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Convertase du TNF-alpha
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Enzyme de conversion du facteur de nécrose tumorale alpha
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Enzyme de conversion du TNF-alpha
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Protéine ADAM-17
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Protéine-17 contenant des domaines désintégrine et métalloprotéinase
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Protéine-17 contenant un domaine désintégrine et un domaine métalloprotéinase
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TACA (Enzyme)
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TACE (Enzyme)
URI
http://data.loterre.fr/ark:/67375/JVR-SL3M8DFH-L
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