Concept information
Término preferido
Lysine Acetyltransferase 5
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Tipo
-
mesh:Descriptor
Definición
- A catalytic subunit of the NuA4 histone acetyltransferase complex that functions in transcriptional activation of genes by acetylation of nucleosomal HISTONES H4 and H2A, altering nucleosome-DNA interactions and interaction of the modified histones with other activating transcription factors. It may control gene expression changes associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest; CELL AGING; APOPTOSIS; and DNA REPAIR. It is polyubiquitinated and degraded during HIV-1 infection through its interaction with the viral TAT PROTEIN.
Concepto genérico
Etiquetas alternativas
- HIV-1-Tat Interactive Protein Tip60
- HTATIP
- KAT5 (TIP60) Protein
En otras lenguas
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francés
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HTATIP
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Lysine acétyltransférase-5
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Protéine KAT5 (TIP60)
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Protéine Tip60 interagissant avec la protéine Tat du virus HIV-1
URI
http://data.loterre.fr/ark:/67375/JVR-QGZV0J2Q-K
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