Concept information
Término preferido
Tensins
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Tipo
-
mesh:Descriptor
Definición
- A family of multidomain microfilament proteins that bind ACTIN FILAMENTS and INTEGRINS at FOCAL ADHESIONS. They generally consist of an N-terminal domain with homology to PHOSPHOTYROSINE PHOSPHATASE, a C2 DOMAIN; unique central regions rich in PROLINE; ALANINE; GLYCINE; and SERINE; an SH2 DOMAIN; and a C-terminal phosphotyrosine-binding region. They are involved in CELL MIGRATION; CELL ADHESION; SIGNAL TRANSDUCTION; and reorganization of the CYTOSKELETON.
Concepto genérico
Etiquetas alternativas
- Tensin
En otras lenguas
-
francés
-
Tensine
URI
http://data.loterre.fr/ark:/67375/JVR-PWL71CNT-X
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