: MeSH: Arsenate Reductases

Enzymes and Coenzymes > Enzymes > Oxidoreductases > Arsenate Reductases

Arsenate Reductases

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Oxidoreductases that specifically reduce arsenate ion to arsenite ion. Reduction of arsenate is a critical step for its biotransformation into a form that can be transported by ARSENITE TRANSPORTING ATPASES or complexed by specific sulfhydryl-containing proteins for the purpose of detoxification (METABOLIC DETOXIFICATION, DRUG). Arsenate reductases require reducing equivalents such as GLUTAREDOXIN or AZURIN. A arsenate reductase that can use azurin as a donor-acceptor. It can use a c-type cytochrome or O(2) as donor-acceptor. An EC classified subtype with unspecified electron acceptor-donor. Reduced glutaredoxin cannot serve as a reductant for this enzyme. Formerly classified as EC 1.97.1.6

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