: MeSH: Telomere Shortening

Chemical Phenomena > Biochemical Phenomena > DNA Replication > Telomere Shortening

Genetic Phenomena > DNA Replication > Telomere Shortening

Cell Physiological Phenomena > Cellular Senescence > Telomere Shortening

Physiological Phenomena > Growth and Development > Aging > Cellular Senescence > Telomere Shortening

Telomere Shortening

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The loss of some TELOMERE sequence during DNA REPLICATION of the first several base pairs of a linear DNA molecule; or from DNA DAMAGE. Cells have various mechanisms to restore length (TELOMERE HOMEOSTASIS.) Telomere shortening is involved in the progression of CELL AGING.

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