Concept information
Término preferido
Factor XII
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Tipo
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mesh:Descriptor
Definición
- Stable blood coagulation factor activated by contact with the subendothelial surface of an injured vessel. Along with prekallikrein, it serves as the contact factor that initiates the intrinsic pathway of blood coagulation. Kallikrein activates factor XII to XIIa. Deficiency of factor XII, also called the Hageman trait, leads to increased incidence of thromboembolic disease. Mutations in the gene for factor XII that appear to increase factor XII amidolytic activity are associated with HEREDITARY ANGIOEDEMA TYPE III.
Concepto genérico
Conceptos específicos
Etiquetas alternativas
- 9001-30-3
- Blood-coagulation factor XII
- Coagulation Factor XII
- Factor 12
- Factor Twelve
- Hageman Factor
En otras lenguas
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francés
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9001-30-3
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Blood-coagulation factor XII
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Facteur de Hageman
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Facteur Hageman
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Facteur XII de la coagulation
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Facteur XII de la coagulation sanguine
URI
http://data.loterre.fr/ark:/67375/JVR-P6Z58324-4
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