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Término preferido

alpha Karyopherins  

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Tipo

  • mesh:Descriptor

Definición

  • Nucleocytoplasmic transport molecules that bind to the NUCLEAR LOCALIZATION SIGNALS of cytoplasmic molecules destined to be imported into the CELL NUCLEUS. Once attached to their cargo they bind to BETA KARYOPHERINS and are transported through the NUCLEAR PORE COMPLEX. Inside the CELL NUCLEUS alpha karyopherins dissociate from beta karypherins and their cargo. They then form a complex with CELLULAR APOPTOSIS SUSCEPTIBILITY PROTEIN and RAN GTP-BINDING PROTEIN which is exported to the CYTOPLASM.

Concepto genérico

Etiquetas alternativas

  • Importin-alpha
  • Karyopherin alpha
  • NLS Receptor
  • NLS-Binding Protein
  • NLSBP
  • Nuclear Localization Sequence Receptor
  • Nuclear Localization Signal-Binding Protein

En otras lenguas

  • francés

  • Cariophérine alpha
  • Kariophérines alpha
  • Protéine de liaison au signal de localisation nucléaire
  • Protéine de liaison du signal de localisation nucléaire
  • Récepteur NLS (Nuclear Localization Signal)

URI

http://data.loterre.fr/ark:/67375/JVR-LV9T29HV-4

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RDF/XML TURTLE JSON-LD Creado 25/7/01, última modificación 12/7/05