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... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Serum Globulins > Beta-Globulins > Properdin
... > Amino Acids, Peptides, and Proteins > Proteins > Globulins > Serum Globulins > Beta-Globulins > Properdin
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Immunoproteins > Complement System Proteins > Properdin

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Properdin  

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Tipo

  • mesh:Descriptor

Definición

  • A 53-kDa protein that is a positive regulator of the alternate pathway of complement activation (COMPLEMENT ACTIVATION PATHWAY, ALTERNATIVE). It stabilizes the ALTERNATIVE PATHWAY C3 CONVERTASE (C3bBb) and protects it from rapid inactivation, thus facilitating the cascade of COMPLEMENT ACTIVATION and the formation of MEMBRANE ATTACK COMPLEX. Individuals with mutation in the PFC gene exhibit properdin deficiency and have a high susceptibility to infections.

Concepto genérico

Etiquetas alternativas

  • 11016-39-0
  • Complement Factor P
  • Complement factor P

En otras lenguas

  • Properdine

    francés

  • 11016-39-0
  • Complement factor P
  • Facteur P du complément

URI

http://data.loterre.fr/ark:/67375/JVR-KH5FR65V-X

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