Concept information
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Peptides
Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
Receptor Protein-Tyrosine Kinases
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Proteins
Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
Receptor Protein-Tyrosine Kinases
Término preferido
Receptor, IGF Type 1
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Tipo
-
mesh:Descriptor
Definición
- A protein-tyrosine kinase receptor that is closely related in structure to the INSULIN RECEPTOR. Although commonly referred to as the IGF-I receptor, it binds both IGF-I and IGF-II with high affinity. It is comprised of a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The beta subunit contains an intrinsic tyrosine kinase domain.
Concepto genérico
Etiquetas alternativas
- IGF Type 1 Receptor
- IGF-1 Receptor
- IGF-I Receptor
- Insulin-Like-Growth Factor I Receptor
- Receptor, IGF-I
- Receptor, Insulin-Like Growth Factor I
- Receptor, Insulin-Like Growth Factor Type 1
- Receptors, IGF-1
- Receptors, Insulin-Like-Growth Factor I
En otras lenguas
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francés
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Récepteur du facteur de croissance 1 analogue à l'insuline
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Récepteur IGF-1
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Récepteurs IGF de type 1
URI
http://data.loterre.fr/ark:/67375/JVR-JMDLC90N-C
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