Concept information
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Peptides
Intracellular Signaling Peptides and Proteins
Adaptor Proteins, Signal Transducing
Nuclear Receptor Coactivators
Término preferido
Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
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Tipo
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mesh:Descriptor
Definición
- A transcriptional co-activator for NUCLEAR RECEPTORS. It is characterized by an N-terminal LxxLL sequence, a region that interacts with PPAR GAMMA, and a C-terminal RNA RECOGNITION MOTIF. It increases expression of MITOCHONDRIAL UNCOUPLING PROTEIN to regulate genes involved in metabolic reprogramming in response to dietary restriction and the integration of CIRCADIAN RHYTHMS with ENERGY METABOLISM.
Concepto genérico
Etiquetas alternativas
- PGC-1-alpha Protein
- PPARGC1a Protein
- PPARGC-1-alpha Protein
En otras lenguas
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francés
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Coactivateur 1-alpha du récepteur gamma activé par les proliférateurs des peroxysomes
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Protéine PGC-1-alpha
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Protéine PPARGC-1-alpha
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Protéine PPARGC1a
URI
http://data.loterre.fr/ark:/67375/JVR-CL3VMSQC-C
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