Concept information
Término preferido
Lovastatin
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Tipo
-
mesh:Descriptor
Definición
- A fungal metabolite isolated from cultures of Aspergillus terreus. The compound is a potent anticholesteremic agent. It inhibits 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It also stimulates the production of low-density lipoprotein receptors in the liver.
Concepto genérico
Conceptos específicos
Etiquetas alternativas
- 6-Methylcompactin
- 75330-75-5 (Lovastatin)
- 9LHU78OQFD
- Mevinolin
- Monacolin K
En otras lenguas
-
francés
-
75330-75-5 (Lovastatin)
-
9LHU78OQFD
URI
http://data.loterre.fr/ark:/67375/JVR-BZNZHQJL-K
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