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Cell Physiological Phenomena > Cell Death > Regulated Cell Death > Apoptosis

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Apoptosis  

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Tipo

  • mesh:Descriptor

Definición

  • A regulated cell death mechanism characterized by distinctive morphologic changes in the nucleus and cytoplasm, including the endonucleolytic cleavage of genomic DNA, at regularly spaced, internucleosomal sites, i.e., DNA FRAGMENTATION. It is genetically programmed and serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth. Apoptosis that is triggered via cell stress and mitochondrial damage. Apoptosis that is triggered via CELL SURFACE RECEPTORS such as TUMOR NECROSIS FACTOR RECEPTORS and DEATH DOMAIN RECEPTORS. Physiological forms of regulated cell death that occur during growth and development and tissue turnover.

Concepto genérico

Conceptos específicos

Conceptos relacionados

Etiquetas alternativas

  • Classic Apoptosis
  • Classical Apoptosis
  • Programmed Cell Death, Type I

En otras lenguas

  • Apoptose

    francés

  • MCP de type I
  • Mort cellulaire apoptotique
  • Mort cellulaire programmée de type 1
  • Mort cellulaire programmée de type I

URI

http://data.loterre.fr/ark:/67375/JVR-BXVMNJSN-S

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