Concept information
Preferred term
Antidepressive Agents, Tricyclic
Type
-
mesh:Descriptor
Definition
- Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However, the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system.
Broader concept
Synonym(s)
- Antidepressant Drugs, Tricyclic
- Antidepressants, Tricyclic
- Tricyclic Antidepressant
- Tricyclic Antidepressant Drug
- Tricyclic Antidepressive Agent
- Tricyclic Antidepressive Agents
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- analysis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Médicaments antidépresseurs tricycliques
URI
http://data.loterre.fr/ark:/67375/JVR-XR0VST6Z-2
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