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Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > Ribosomal Protein S6 Kinases
Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > Ribosomal Protein S6 Kinases
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Protein Kinases > Protein Serine-Threonine Kinases > Ribosomal Protein S6 Kinases

Preferred term

Ribosomal Protein S6 Kinases  

Type

  • mesh:Descriptor

Definition

  • A family of protein serine/threonine kinases which act as intracellular signalling intermediates. Ribosomal protein S6 kinases are activated through phosphorylation in response to a variety of HORMONES and INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS. Phosphorylation of RIBOSOMAL PROTEIN S6 by enzymes in this class results in increased expression of 5' top MRNAs. Although specific for RIBOSOMAL PROTEIN S6 members of this class of kinases can act on a number of substrates within the cell. The immunosuppressant SIROLIMUS inhibits the activation of ribosomal protein S6 kinases.

Broader concept

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Synonym(s)

  • Ribosomal Protein S6 Kinase
  • S6-H4 Kinase
  • S6 Kinase

Allowable Qualifier(s)

In other languages

  • Ribosomal Protein S6 Kinases

    French

  • Kinases des protéines ribosomiales S6
  • Kinases des protéines ribosomiques S6
  • Kinases RSK
  • Protéines ribosomiques S6 kinases
  • S6 kinases

URI

http://data.loterre.fr/ark:/67375/JVR-VM70TMSC-B

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RDF/XML TURTLE JSON-LD Created 6/20/97, last modified 6/10/21