Skip to main content

Medical Subject Headings (thesaurus)

Search from vocabulary

  • Help
align
annotate
download

Concept information

Amino Acids, Peptides, and Proteins > Proteins > Antiviral Restriction Factors > Interferon-Induced Helicase, IFIH1
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Nucleotidyltransferases > RNA Nucleotidyltransferases > RNA Helicases > DEAD-box RNA Helicases > Interferon-Induced Helicase, IFIH1

Preferred term

Interferon-Induced Helicase, IFIH1  

Type

  • mesh:Descriptor

Definition

  • A DEAD box RNA helicase that contains two N-terminal CASPASE ACTIVATION AND RECRUITMENT DOMAINS. It functions as a sensor of viral NUCLEIC ACIDS such as DOUBLE-STRANDED RNA and activates the INNATE IMMUNE RESPONSE by inducing the expression of INTERFERON-ALPHA and INTERFERON-BETA. It may also regulate cell growth and APOPTOSIS.

Broader concept

Synonym(s)

  • CADM-140 Autoantigen
  • Helicard
  • IFIH1 Protein
  • Interferon-Induced Helicase C Domain-Containing Protein 1
  • Interferon Induced with Helicase C Domain 1
  • Melanoma Differentiation-Associated Protein 5

Allowable Qualifier(s)

In other languages

  • Hélicase IFIH1 inductrice de l'interféron

    French

  • Auto-antigène CADM-140
  • Autoantigène CADM-140
  • Helicard
  • Interferon-induced helicase C domain-containing protein 1
  • Interferon-induced helicase IFIH1
  • Protéine IFIH1
  • Protéine-5 associée à la différenciation du mélanome

URI

http://data.loterre.fr/ark:/67375/JVR-VDJRM949-M

Download this concept:

RDF/XML TURTLE JSON-LD Created 7/8/16, last modified 5/10/21