Concept information
Preferred term
Receptor, Interferon alpha-beta
Type
-
mesh:Descriptor
Definition
- A ubiquitously expressed heterodimeric receptor that is specific for both INTERFERON-ALPHA and INTERFERON-BETA. It is composed of two subunits referred to as IFNAR1 and IFNAR2. The IFNAR2 subunit is believed to serve as the ligand-binding chain; however both chains are required for signal transduction. The interferon alpha-beta receptor signals through the action of JANUS KINASES such as the TYK2 KINASE. A shortened cytoplasmic domain variant of the IFNAR2 chain. The full-length variant of the IFNAR2 chain.
Broader concept
Synonym(s)
- 156986-95-7
- IFN-alphabetaR
- IFN-alphaR
- Interferon alpha-beta Receptor
- Interferon alphabeta Receptors
- Interferon alpha Receptor
- Interferon alpha Receptors
- Receptor, Interferon alpha
- Type I Interferon Receptor
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- physiology (Qualifier)
- radiation effects (Qualifier)
- therapeutic use (Qualifier)
- ultrastructure (Qualifier)
In other languages
-
French
-
156986-95-7
-
Récepteur à l'IFN alpha
-
Récepteur à l'IFN alpha/bêta
-
Récepteur à l'IFN de type I
-
Récepteur à l'interféron de type I
-
Récepteur de l'interféron alpha-bêta
-
Récepteur de l'interféron de type I
URI
http://data.loterre.fr/ark:/67375/JVR-SRGMXRVG-B
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