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Concept information

Preferred term

Troglitazone  

Type

  • mesh:Descriptor

Definition

  • A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.

Synonym(s)

  • 2,4-Thiazolidinedione, 5-((4-((3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy)phenyl)methyl)-
  • 5-(4-((6-Hydroxy-2,5,7,8-tetramethylchroman-2-yl-methoxy)benzyl)-2,4-thiazolidinedione) - T
  • 97322-87-7 (Troglitazone)
  • I66ZZ0ZN0E

Pharmacological Action(s)

In other languages

  • French

  • 2,4-Thiazolidinedione, 5-((4-((3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy)phenyl)methyl)-
  • 97322-87-7 (Troglitazone)
  • I66ZZ0ZN0E

URI

http://data.loterre.fr/ark:/67375/JVR-SKKVSRN3-5

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RDF/XML TURTLE JSON-LD Created 7/9/18, last modified 2/27/18