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Pathological Conditions, Signs and Symptoms > Pathologic Processes > Chromosome Aberrations > Isochromosomes
Genetic Phenomena > Genetic Variation > Mutation > Chromosome Aberrations > Isochromosomes
Genetic Phenomena > Genetic Structures > Chromosomes > Isochromosomes
... > Cells > Cellular Structures > Intracellular Space > Cytoplasm > Cytoplasmic Structures > Organelles > Cell Nucleus > Cell Nucleus Structures > Intranuclear Space > Chromosomes > Isochromosomes
... > Fluids and Secretions > Body Fluids > Body Fluid Compartments > Intracellular Space > Cytoplasm > Cytoplasmic Structures > Organelles > Cell Nucleus > Cell Nucleus Structures > Intranuclear Space > Chromosomes > Isochromosomes
... > Tissues > Body Fluid Compartments > Intracellular Space > Cytoplasm > Cytoplasmic Structures > Organelles > Cell Nucleus > Cell Nucleus Structures > Intranuclear Space > Chromosomes > Isochromosomes

Preferred term

Isochromosomes  

Type

  • mesh:Descriptor

Definition

  • Metacentric chromosomes produced during MEIOSIS or MITOSIS when the CENTROMERE splits transversely instead of longitudinally. The chromosomes produced by this abnormal division are one chromosome having the two long arms of the original chromosome, but no short arms, and the other chromosome consisting of the two short arms and no long arms. Each of these isochromosomes constitutes a simultaneous duplication and deletion.

Broader concept

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URI

http://data.loterre.fr/ark:/67375/JVR-S41FJ14G-F

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RDF/XML TURTLE JSON-LD Created 1/25/94, last modified 7/8/08