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Concept information

Preferred term

Granulocyte Colony-Stimulating Factor  

Type

  • mesh:Descriptor

Definition

  • A glycoprotein of MW 25 kDa containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines.

Narrower concepts

Synonym(s)

  • 143011-72-7
  • Colony-stimulating factor, granulocyte
  • G-CSF

In other languages

  • French

  • 143011-72-7
  • Colony-stimulating factor, granulocyte
  • Facteur de croissance des colonies granulocytaires
  • Facteur de croissance des granulocytes
  • Facteur de croissance granulocytaire
  • Facteur stimulant la formation de colonies de granulocytes neutrophiles
  • Facteur stimulant la formation de colonies de neutrophiles
  • Facteur stimulant les colonies de granulocytes
  • G-CSF
  • GCSF

URI

http://data.loterre.fr/ark:/67375/JVR-RXM7WLB1-5

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RDF/XML TURTLE JSON-LD Created 6/19/90, last modified 6/24/11