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... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Oxygenases > Mixed Function Oxygenases > Cytochrome P-450 Enzyme System > Steroid Hydroxylases > Cholesterol Side-Chain Cleavage Enzyme
... > Amino Acids, Peptides, and Proteins > Proteins > Hemeproteins > Cytochromes > Cytochrome P-450 Enzyme System > Steroid Hydroxylases > Cholesterol Side-Chain Cleavage Enzyme
Enzymes and Coenzymes > Cytochromes > Cytochrome P-450 Enzyme System > Steroid Hydroxylases > Cholesterol Side-Chain Cleavage Enzyme
... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Oxygenases > Mixed Function Oxygenases > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 11 > Cholesterol Side-Chain Cleavage Enzyme
... > Amino Acids, Peptides, and Proteins > Proteins > Hemeproteins > Cytochromes > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 11 > Cholesterol Side-Chain Cleavage Enzyme
Enzymes and Coenzymes > Cytochromes > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 11 > Cholesterol Side-Chain Cleavage Enzyme

Preferred term

Cholesterol Side-Chain Cleavage Enzyme  

Type

  • mesh:Descriptor

Definition

  • A mitochondrial cytochrome P450 enzyme that catalyzes the side-chain cleavage of C27 cholesterol to C21 pregnenolone in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP11A1 gene, catalyzes the breakage between C20 and C22 which is the initial and rate-limiting step in the biosynthesis of various gonadal and adrenal steroid hormones.

Broader concept

Synonym(s)

  • 20,22-Desmolase
  • Cholesterol Desmolase
  • Cholesterol Monooxygenase (Side-Chain-Cleaving)
  • Cholesterol,reduced-adrenal-ferredoxin:oxygen oxidoreductase (side-chain-cleaving)
  • CYP 11A1
  • CYP11A1
  • Cytochrome P450 11A1
  • Cytochrome P-450 CYP11A1
  • Cytochrome P-450(scc)
  • Cytochrome P450scc

Allowable Qualifier(s)

In other languages

  • Cholesterol side-chain cleavage enzyme

    French

  • 20,22-Desmolase
  • Cholesterol desmolase
  • Cholesterol monooxygenase (side-chain-cleaving)
  • Cholesterol,reduced-adrenal-ferredoxin:oxygen oxidoreductase (side-chain-cleaving)
  • CYP 11A1
  • CYP11A1
  • Cytochrome P-450 CYP11A1
  • Cytochrome P-450(scc)
  • Cytochrome P450 11A1
  • Cytochrome P450scc
  • Enzyme de clivage de la chaine latérale du cholestérol
  • Enzyme de clivage de la chaîne latérale du cholestérol

URI

http://data.loterre.fr/ark:/67375/JVR-RP35J4PP-3

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