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... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Serum Globulins > Immunoglobulins > Antibodies > Antibodies, Monoclonal > Antibodies, Monoclonal, Humanized > Omalizumab
... > Amino Acids, Peptides, and Proteins > Proteins > Globulins > Serum Globulins > Immunoglobulins > Antibodies > Antibodies, Monoclonal > Antibodies, Monoclonal, Humanized > Omalizumab
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Immunoproteins > Immunoglobulins > Antibodies > Antibodies, Monoclonal > Antibodies, Monoclonal, Humanized > Omalizumab
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Serum Globulins > Immunoglobulins > Antibodies > Antibodies, Anti-Idiotypic > Omalizumab
... > Amino Acids, Peptides, and Proteins > Proteins > Globulins > Serum Globulins > Immunoglobulins > Antibodies > Antibodies, Anti-Idiotypic > Omalizumab
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Immunoproteins > Immunoglobulins > Antibodies > Antibodies, Anti-Idiotypic > Omalizumab

Preferred term

Omalizumab  

Type

  • mesh:Descriptor

Definition

  • An anti-IgE, recombinant, humanized monoclonal antibody which specifically binds to the C epsilon3 domain of IMMUNOGLOBULIN E, the site of high-affinity IgE receptor binding. It inhibits the binding of IgE to MAST CELLS and BASOPHILS to reduce the severity of the allergic response and is used in the management of persistent allergic ASTHMA.

Broader concept

Synonym(s)

  • 242138-07-4
  • 2P471X1Z11
  • Immunoglobulin G, anti-(human immunoglobulin E Fc region)(human-mouse monoclonal E25 clone pSVIE26 gamma-chain), disulfide with human-mouse monoclonal E25 clone pSVIE26 kappa-chain, dimer

Allowable Qualifier(s)

Pharmacological Action(s)

In other languages

  • Omalizumab

    French

  • 242138-07-4
  • 2P471X1Z11
  • Immunoglobulin G, anti-(human immunoglobulin E Fc region)(human-mouse monoclonal E25 clone pSVIE26 gamma-chain), disulfide with human-mouse monoclonal E25 clone pSVIE26 kappa-chain, dimer

URI

http://data.loterre.fr/ark:/67375/JVR-QS194GCH-N

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RDF/XML TURTLE JSON-LD Created 7/1/15, last modified 6/20/17