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Amino Acids, Peptides, and Proteins > Proteins > Glycoproteins > Membrane Glycoproteins > Histocompatibility Antigens Class I
Carbohydrates > Glycoconjugates > Glycoproteins > Membrane Glycoproteins > Histocompatibility Antigens Class I
Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Glycoproteins > Histocompatibility Antigens Class I
Biological Factors > Antigens > Antigens, Surface > Histocompatibility Antigens > Histocompatibility Antigens Class I
Biological Factors > Antigens > Isoantigens > Histocompatibility Antigens > Histocompatibility Antigens Class I

Preferred term

Histocompatibility Antigens Class I  

Type

  • mesh:Descriptor

Definition

  • Membrane glycoproteins consisting of an alpha subunit and a BETA 2-MICROGLOBULIN beta subunit. In humans, highly polymorphic genes on CHROMOSOME 6 encode the alpha subunits of class I antigens and play an important role in determining the serological specificity of the surface antigen. Class I antigens are found on most nucleated cells and are generally detected by their reactivity with alloantisera. These antigens are recognized during GRAFT REJECTION and restrict cell-mediated lysis of virus-infected cells.

Broader concept

Narrower concepts

Related concepts

Synonym(s)

  • Class I Antigen
  • Class I Antigens
  • Class I Histocompatibility Antigen
  • Class I Histocompatibility Antigens
  • Class I Major Histocompatibility Antigen
  • Class I Major Histocompatibility Antigens
  • Class I Major Histocompatibility Molecules
  • Class I MHC Protein
  • Class I MHC Proteins
  • MHC Class I Molecule
  • MHC Class I Molecules
  • MHC-I Molecules
  • MHC-I Peptide
  • MHC-I Peptides

Allowable Qualifier(s)

In other languages

  • Antigènes d'histocompatibilité de classe I

    French

  • Antigène d'histocompatibilité classe I
  • Antigène d'histocompatibilité de classe I
  • Antigènes d'histocompatibilité de classe 1
  • Antigènes d'histocompatibilité majeure de classe I
  • Antigènes de classe I
  • Antigènes de classe I du complexe majeur d'histocompatibilité
  • Antigènes du CMH de classe I
  • Antigènes majeurs d'histocompatibilité de classe I

URI

http://data.loterre.fr/ark:/67375/JVR-QG10Z2C8-P

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