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... > Biological Factors > Antigens > Antigens, Surface > Antigens, Differentiation > Antigens, Differentiation, T-Lymphocyte > Programmed Cell Death 1 Receptor
Biological Factors > Biomarkers > Antigens, Differentiation > Antigens, Differentiation, T-Lymphocyte > Programmed Cell Death 1 Receptor
Biological Factors > Immune Checkpoint Proteins > Programmed Cell Death 1 Receptor
Amino Acids, Peptides, and Proteins > Proteins > Immune Checkpoint Proteins > Programmed Cell Death 1 Receptor
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Costimulatory and Inhibitory T-Cell Receptors > Programmed Cell Death 1 Receptor

Preferred term

Programmed Cell Death 1 Receptor  

Type

  • mesh:Descriptor

Definition

  • An inhibitory T-lymphocyte receptor that has specificity for CD274 ANTIGEN and PROGRAMMED CELL DEATH 1 LIGAND 2 PROTEIN. Signaling by the receptor limits T cell proliferation and INTERFERON GAMMA synthesis. The receptor also may play an essential role in the regulatory pathway that induces PERIPHERAL TOLERANCE.

Broader concept

Related concepts

Synonym(s)

  • Antigens, CD279
  • CD279 Antigen
  • PD-1 Protein
  • PD-1 Receptor
  • PD1 Receptor
  • Programmed Cell Death 1 Protein
  • Programmed Cell Death Protein 1

Allowable Qualifier(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-QF0LTPK7-6

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RDF/XML TURTLE JSON-LD Created 6/24/11, last modified 3/27/20