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Concept information

Preferred term

Core Binding Factor alpha Subunits  

Type

  • mesh:Descriptor

Definition

  • A family of transcription factors that bind to the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. Family members contain a highly conserved DNA-binding domain known as the runt domain. They can act as both activators and repressors of expression of GENES involved in CELL DIFFERENTIATION and CELL CYCLE progression.

Broader concept

Synonym(s)

  • Acute Myeloid Leukemia Proteins
  • Core Binding Factor alpha Proteins
  • PEBP2A Transcription Factors
  • Polyomavirus Enhancer A Binding Protein 2
  • Polyomavirus Enhancer Binding Protein 2, Alpha Subunit
  • Runt Domain Factor
  • Runx Proteins

In other languages

  • French

  • Acute myeloid leukemia proteins
  • Core binding factor alpha subunits
  • Facteur de transcription à domaine Runt
  • Facteurs de transcription AML
  • Facteurs de transcription CBF-alpha
  • Facteurs de transcription CBF/AML
  • Facteurs de transcription PEBP2A
  • Polyomavirus enhancer A binding protein 2
  • Polyomavirus enhancer binding protein 2 alpha subunit
  • Protéines AML
  • Protéines CBF-alpha
  • Protéines Runx

URI

http://data.loterre.fr/ark:/67375/JVR-Q4LZ57KX-B

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RDF/XML TURTLE JSON-LD Created 6/30/05, last modified 7/9/13