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Biological Factors > Antigens > Autoantigens > Heymann Nephritis Antigenic Complex

Preferred term

Heymann Nephritis Antigenic Complex  

Type

  • mesh:Descriptor

Definition

  • A complex of antigenic proteins obtained from the brush border of kidney tubules. It contains two principal components LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-2 and LDL-RECEPTOR RELATED PROTEIN-ASSOCIATED PROTEIN. The name of this complex is derived from researcher, Dr. Walter Heymann, who developed an experimental model of membranous glomerulonephritis (GLOMERULONEPHRITIS) by injecting this antigenic complex into rats to induce an autoimmune response. A specific preparation of Heymann nephritis antigenic complex.

Broader concept

Synonym(s)

  • Heymann's Antigen
  • Nephritis Antigen, Heyman
  • Nephritogenic Antigen
  • Receptor-Associated Protein, Heymann Nephritis

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-P4MTL33N-T

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RDF/XML TURTLE JSON-LD Created 7/25/01, last modified 7/1/11