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... > Cells > Cellular Structures > Intracellular Space > Cytoplasm > Cytoplasmic Structures > Organelles > Cell Nucleus > Cell Nucleus Structures > Intranuclear Space > Nuclear Bodies > Promyelocytic Leukemia Nuclear Bodies
... > Fluids and Secretions > Body Fluids > Body Fluid Compartments > Intracellular Space > Cytoplasm > Cytoplasmic Structures > Organelles > Cell Nucleus > Cell Nucleus Structures > Intranuclear Space > Nuclear Bodies > Promyelocytic Leukemia Nuclear Bodies
... > Tissues > Body Fluid Compartments > Intracellular Space > Cytoplasm > Cytoplasmic Structures > Organelles > Cell Nucleus > Cell Nucleus Structures > Intranuclear Space > Nuclear Bodies > Promyelocytic Leukemia Nuclear Bodies

Preferred term

Promyelocytic Leukemia Nuclear Bodies  

Type

  • mesh:Descriptor

Definition

  • Spherical intranuclear membraneless bodies nucleated by PROMYELOCYTIC LEUKEMIA PROTEIN and various other proteins containing small ubiquitin-related modifier (SUMO) interaction motif (SIM) and/or sumoylated proteins (e.g., Sp100 protein). Promyelocytic leukemia nuclear bodies regulate posttranslational modifications of partner proteins (e.g., SUMOYLATION) which in turn lead to modulation of various biological processes.

Broader concept

Synonym(s)

  • PML Bodies
  • PML NBs
  • PML Nuclear Bodies
  • Promyelocytic Leukemia Nuclear Body
  • Promyelocytic Leukemia Protein Bodies
  • Promyelocytic Leukemia Protein Body

Allowable Qualifier(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-P43Q3SK5-S

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RDF/XML TURTLE JSON-LD Created 7/9/21, last modified 7/1/21