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... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptor Protein-Tyrosine Kinases > Receptor, Insulin
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein-Tyrosine Kinases > Receptor Protein-Tyrosine Kinases > Receptor, Insulin
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein-Tyrosine Kinases > Receptor Protein-Tyrosine Kinases > Receptor, Insulin
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Protein Kinases > Protein-Tyrosine Kinases > Receptor Protein-Tyrosine Kinases > Receptor, Insulin
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Peptide > Receptors, Pancreatic Hormone > Receptor, Insulin

Preferred term

Receptor, Insulin  

Type

  • mesh:Descriptor

Definition

  • A cell surface receptor for INSULIN. It comprises a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The receptor contains an intrinsic TYROSINE KINASE domain that is located within the beta subunit. Activation of the receptor by INSULIN results in numerous metabolic changes including increased uptake of GLUCOSE into the liver, muscle, and ADIPOSE TISSUE.

Broader concept

Related concepts

Synonym(s)

  • Insulin-Dependent Tyrosine Protein Kinase
  • Insulin Receptor
  • Insulin Receptor Protein-Tyrosine Kinase
  • Receptors, Insulin

Allowable Qualifier(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-P0LBW056-3

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RDF/XML TURTLE JSON-LD Created 5/3/76, last modified 5/21/21