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Concept information

Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein-Tyrosine Kinases > Agammaglobulinaemia Tyrosine Kinase
Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein-Tyrosine Kinases > Agammaglobulinaemia Tyrosine Kinase
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Protein Kinases > Protein-Tyrosine Kinases > Agammaglobulinaemia Tyrosine Kinase

Preferred term

Agammaglobulinaemia Tyrosine Kinase  

Type

  • mesh:Descriptor

Definition

  • A non-receptor tyrosine kinase that is essential for the development, maturation, and signaling of B-LYMPHOCYTES. It contains an N-terminal zinc finger motif and localizes primarily to the PLASMA MEMBRANE and nucleus of B-lymphocytes. Mutations in the gene that encode this kinase are associated with X-LINKED AGAMMAGLOBULINEMIA.

Broader concept

Synonym(s)

  • B Cell Progenitor Kinase
  • Bruton's Tyrosine Kinase

Allowable Qualifier(s)

In other languages

  • Agammaglobulinaemia tyrosine kinase

    French

  • B cell progenitor kinase
  • Bruton's tyrosine kinase
  • Kinase des progéniteurs des cellules B
  • Kinase des progéniteurs des lymphocytes B
  • Tyrosine kinase de Bruton
  • Tyrosine kinase de l'agammaglobulinémie

URI

http://data.loterre.fr/ark:/67375/JVR-MT0TM4WH-W

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RDF/XML TURTLE JSON-LD Created 7/9/18, last modified 5/20/21