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Concept information

Preferred term

Glaucarubin  

Type

  • mesh:Descriptor

Definition

  • (1 beta,2 alpha,11 beta,12 alpha,15 beta(S))-11,20-Epoxy-1,2,11,12-tetrahydroxy-15-(2-hydroxy-2-methyl-1-oxobutoxy)picras-3-en-16-one. A quassinoid (Simaroubolide) from Simaruba glauca, a tropical shrub. It has been used as an antiamebic agent and is found to be cytotoxic. It may be of use in cancer chemotherapy.

Broader concept

Synonym(s)

  • 1448-23-3 (Glaucarubin)
  • EH6H7VS52J
  • Kirondrin
  • Picras-3-en-16-one, 11,20-epoxy-1,2,11,12-tetrahydroxy-15-(2-hydroxy-2-methyl-1-oxobutoxy)-, (1beta,2alpha,11beta,12alpha,15beta(S))-

Pharmacological Action(s)

In other languages

  • French

  • 1448-23-3 (Glaucarubin)
  • EH6H7VS52J
  • Picras-3-en-16-one, 11,20-epoxy-1,2,11,12-tetrahydroxy-15-(2-hydroxy-2-methyl-1-oxobutoxy)-, (1beta,2alpha,11beta,12alpha,15beta(S))-

URI

http://data.loterre.fr/ark:/67375/JVR-MSKXDZVP-4

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