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Concept information

Preferred term

NLR Proteins  

Type

  • mesh:Descriptor

Definition

  • Intracellular signaling proteins that are defined by the presence of a NUCLEOTIDE-binding region and LEUCINE-rich repeats. Their general structure consists of any of a variety of effector domains at their N-termini such as a caspase recruitment domain (CARD), a central nucleotide-binding domain, and a variable number of C-terminal leucine-rich repeats. They are important for pathogen recognition in the INNATE IMMUNE RESPONSE of animals and plants. Members of the NLR protein family include the NOD SIGNALING ADAPTOR PROTEINS.

Synonym(s)

  • NLR Protein
  • NOD-like Receptor
  • NOD-like Receptors
  • Nucleotide-Binding Domain Leucine-Rich Repeat Protein
  • Nucleotide-binding Domain Leucine-rich Repeat Proteins

In other languages

  • French

  • Protéine NLR
  • Protéines portant un domaine liant les nucléotides et une répétition riche en leucine
  • Récepteurs analogues à NOD
  • Récepteurs semblables à NOD
  • Récepteurs similaires à NOD

URI

http://data.loterre.fr/ark:/67375/JVR-MQRWZGD9-T

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RDF/XML TURTLE JSON-LD Created 7/8/16, last modified 5/27/20