Skip to main content

Medical Subject Headings (thesaurus)

Search from vocabulary

align
annotate
download

Concept information

Amino Acids, Peptides, and Proteins > Proteins > Cytoskeletal Proteins > Intermediate Filament Proteins > Keratins
... > Technology, Industry, and Agriculture > Manufactured Materials > Biomedical and Dental Materials > Polymers > Biopolymers > Intermediate Filament Proteins > Keratins
... > Chemical Actions and Uses > Specialty Uses of Chemicals > Biomedical and Dental Materials > Polymers > Biopolymers > Intermediate Filament Proteins > Keratins
Macromolecular Substances > Polymers > Biopolymers > Intermediate Filament Proteins > Keratins
Amino Acids, Peptides, and Proteins > Proteins > Scleroproteins > Keratins

Preferred term

Keratins  

Type

  • mesh:Descriptor

Definition

  • A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.

Broader concept

Narrower concepts

Related concepts

Synonym(s)

  • 68238-35-7
  • 9008-18-8 (other number)
  • Cytokeratin
  • Keratin

Allowable Qualifier(s)

In other languages

  • Kératines

    French

  • 68238-35-7
  • 9008-18-8 (other number)
  • Cytokératines

URI

http://data.loterre.fr/ark:/67375/JVR-MH528X6P-B

Download this concept:

RDF/XML TURTLE JSON-LD Created 1/1/99, last modified 5/27/20