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Chemical Actions and Uses > Pharmacologic Actions > Molecular Mechanisms of Pharmacological Action > Enzyme Inhibitors > Cholinesterase Inhibitors
... > Chemical Actions and Uses > Pharmacologic Actions > Molecular Mechanisms of Pharmacological Action > Neurotransmitter Agents > Cholinergic Agents > Cholinesterase Inhibitors
... > Chemical Actions and Uses > Pharmacologic Actions > Physiological Effects of Drugs > Neurotransmitter Agents > Cholinergic Agents > Cholinesterase Inhibitors

Preferred term

Cholinesterase Inhibitors  

Type

  • mesh:Descriptor

Definition

  • Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.

Broader concept

Related concepts

Synonym(s)

  • Anti-Cholinesterase
  • Anticholinesterase
  • Anticholinesterase Agent
  • Anticholinesterase Agents
  • Anticholinesterase Drug
  • Anticholinesterase Drugs
  • Anti-Cholinesterases
  • Anticholinesterases
  • Cholinesterase Inhibitor

Allowable Qualifier(s)

In other languages

  • Anticholinestérasiques

    French

  • Anti-cholinestérases
  • Anti-cholinestérasiques
  • Anticholinestérases
  • Inhibiteurs de la cholinestérase
  • Médicaments anticholinestérasiques

URI

http://data.loterre.fr/ark:/67375/JVR-LZK1MWDJ-0

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