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Concept information

... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > Caspases > Caspases, Initiator > Caspase 12
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > Caspases > Caspases, Initiator > Caspase 12
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Cysteine Proteases > Cysteine Endopeptidases > Caspases > Caspases, Initiator > Caspase 12
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Endopeptidases > Cysteine Endopeptidases > Caspases > Caspases, Initiator > Caspase 12

Preferred term

Caspase 12  

Type

  • mesh:Descriptor

Definition

  • A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Caspase 12 is activated by pro-apoptotic factors that are released during cell stress and by CARD SIGNALING ADAPTOR PROTEINS. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES.

Broader concept

Synonym(s)

  • Caspase-12

Allowable Qualifier(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-LD4SGGSL-J

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RDF/XML TURTLE JSON-LD Created 7/5/06, last modified 5/21/21