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Concept information

Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > rho-Associated Kinases
Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > rho-Associated Kinases
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Protein Kinases > Protein Serine-Threonine Kinases > rho-Associated Kinases

Preferred term

rho-Associated Kinases  

Type

  • mesh:Descriptor

Definition

  • A group of intracellular-signaling serine threonine kinases that bind to RHO GTP-BINDING PROTEINS. They were originally found to mediate the effects of rhoA GTP-BINDING PROTEIN on the formation of STRESS FIBERS and FOCAL ADHESIONS. Rho-associated kinases have specificity for a variety of substrates including MYOSIN-LIGHT-CHAIN PHOSPHATASE and LIM KINASES.

Broader concept

Synonym(s)

  • rho-Associated Coiled-Coil Kinase
  • rho-Associated Kinase
  • rho-Kinase
  • ROCK Protein Kinases
  • ROK Kinase

Allowable Qualifier(s)

In other languages

  • rho-Associated Kinases

    French

  • Kinase rho
  • Protéine kinases ROCK
  • rho-Associated Coiled-Coil Kinase
  • rho-Kinase
  • ROCK Protein Kinases
  • ROK Kinase

URI

http://data.loterre.fr/ark:/67375/JVR-K220QL4D-9

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RDF/XML TURTLE JSON-LD Created 7/9/07, last modified 5/21/21